Search on: LACTOSE SYNTHASE 
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Descriptor English:   Lactose Synthase 
Descriptor Spanish:   Lactosa Sintasa 
Descriptor Portuguese:   Lactose Sintase 
Synonyms English:   Lactose Synthetase  
Tree Number:   D08.811.600.541
D08.811.913.400.450.400.500
Definition English:   An enzyme of the transferase class that catalyzes the transfer of galactose from UDPgalactose to glucose, forming lactose. The enzyme is a complex of the enzyme N-ACETYLLACTOSAMINE SYNTHASE and alpha-lactalbumin; the latter protein is present in lactating mammary gland cells where it alters the usual specificity of the former to make lactose synthesis the preferred reaction. (Dorland, 28th ed) EC 2.4.1.22. 
History Note English:   92: was LACTOSE SYNTHETASE 1972-91 (Prov 1972-73) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   30378 
Unique Identifier:   D007788 

Occurrence in VHL:
 

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